Search results for " Generic"

Rivestimenti di varietà algebriche contenuti in fibrati di piani proiettivi

Współczesna metropolia: tożsamość i formy bycia razem jej mieszkańców

2018

The following paper examines the Baumanian “forms of togethernes” in the space of the contemporary metropolis, both in the West (Europe, the USA), and the developing world (China). Zygmunt Bauman understands togetherness as a totality of interhuman actions, occurring in the city space. Paradoxically, the contemporary metropolis which often seems hostile towards traditional bourgeois urban life opens up new possibilities of mutual relations between contemporary citizens. The space in the contemporary city is neither fully artificial, nor natural, but it merges some features of both. Although its infrastructure is governed by effectiveness of molecular capitalism, it is not fully predicable i…

Clinical review: impact of statin substitution policies on patient outcomes.

2009

Background. The increasing awareness of cost issues in health care has led to the increasing use of policy-driven substitution of branded for generic medications, particularly relative to statin treatment for cardiovascular diseases. While there are potential short-term health care savings, the consequences for primary care are under-researched. Our objective was to review data on intensive statin therapy and generic substitution in patients at high cardiovascular risk. Results. Current treatment guidelines for the prevention of cardiovascular disease are consistent in their recommendations regarding statin therapy and treatment targets. Clinical trials demonstrate that to reduce cardiovasc…

Osservatorio della Corte costituzionale (n. 7/2011)

2011

Corte cost. n. 183 del 2011 (in tema di attenuanti generiche, condotta susseguente al reato e rigidi automatismi)

Enhancing performance of α‐diiminonickel precatalyst for ethylene polymerization by substitution with the 2,4‐bis(4,4'‐dimethoxybenzhydryl)‐6‐methylp…

2020

High activities in ethylene polymerization predetermine α‐diiminonickel precatalysts for potential industrial applications. In our study, we have synthesized and characterized a series of unsymmetrical 1‐(2,4‐bis(4,4′‐dimethoxybenzhydryl)‐6‐MeC6H2N)‐2‐arylimino‐acenaphthylene nickel(II) halides. The single‐crystal X‐ray diffraction study of representative compounds reveals distorted tetrahedral geometry. On activation with either Me2AlCl or modified methylaluminoxane, these nickel complexes exhibit high activities of the order of 106 g of PE (mol of Ni)−1 h−1 and produce polyethylene of generic application characterized by high molecular weight, narrow molecular weight distribution, and mod…

Competitive advantage in a global market: The Case of the Norwegian Salmon Farming Industry A comparative study of the Chilean salmon farming industry

2018

Master's thesis Business Administration BE501 - University of Agder 2018 Purpose – This study tries to address the differentiation done by a mature industry as a comparative study to Felzensztein and Gimmon´s (2014) paper on the Chilean farmed salmon industry. It focuses on how firms might improve their performance in an international context. Choosing between either cost-advantage or differentiation as a form gaining a competitive advantage, this study further addresses the usage of the country of origin effect as a form of differentiation. Design/Methodology/Approach – The research unit of the thesis is set in the Norwegian salmon farming industry, alas the biggest producer of salmon in t…

Generic vancomycin products: Analysis of serum concentrations in patients with acute myeloid leukemia.

2013

Summary Concerns have recently emerged about the quality of generic vancomycin products. Our aim is to analyze serum vancomycin concentrations measured 48 hours after the start of an empirical treatment regimen in patients with acute myeloid leukemia (AML) who received one of the two generic vancomycin products available in France. Patients and methods Seventy-nine AML patients treated with vancomycin during two study periods were included in the study. Our vancomycin dosing regimen was based on the patients’ total body weight adjusted for renal clearance. Results A total of 93 serum vancomycin concentrations were collected: 31 in period 1 and 62 in period 2. In bivariate analysis, the mean…

Biosimilar and generic formulations of novel antidiabetic drugs: the role of liraglutide in clinical pharmacology of type 2 diabetes.

2022

Retrospective evaluation of persistence in osteoporosis therapy with oral bisphosphonates in Italy: the TOBI study

2019

The patients’ persistence with osteoporosis treatments is low. This retrospective, multicenter survey showed that almost 30% of osteoporotic patients discontinued the treatment within the first 6 months and that those taking drinkable bisphosphonates were less likely to interrupt the therapy; instead, the use of generic bisphosphonates was associated to a more precocious interruption. Purpose: Low persistence with osteoporosis medications is associated with higher fracture risk. This study aimed to assess the persistence to treatment with oral bisphosphonates among Italian osteoporotic patients under treatment for at least 6 months and to evaluate whether the different oral formulations of …

Patterns and trends in scientific research on generic drugs

2016

[Purpose]: The purpose of this study to investigate the evolution and current status of peer-reviewed publications concerning generic drugs during the past few decades. [Methods]: Scientific articles about generic drugs published until 2012 were retrieved through the PubMed/MEDLINE database, and a content analysis was performed. [Findings]: Our study revealed an increasing number of publications on generics since 1984. Statins, antiretroviral therapies, and antiepileptics, followed by immunosuppressants and antithrombotic agents, were the most common therapeutic drug categories. [Implications]: Almost 60% of the generics detailed in studies indexed in MEDLINE were acting on the cardiovascul…